Son Heung-min returns to the Tottenham Hotspur starting XI this afternoon but Gareth Bale once again has to content himself with a place among the substitutes.
Manchester United are the visitors to north London, where the action gets under way at 16:30 BST.
Son is one of three players recalled to Jose Mourinho’s side, with the other two changes occuring in defence.
Eric Dier and Serge Aurier are brought into the back four as Davinson Sanchez, Japhet Tanganga and Carlos Vinicius make way.
Manchester United make three changes from the side that beat Granada 2-0 on Thursday night but compared to Gameweek 31, Ole Gunnar Solskjaer’s starting XI shows just one tweak.
Scott McTominay is recalled, with Mason Greenwood dropping to the bench.
That means that David de Gea is once again only among the substitutes, with Dean Henderson lining up between the posts.
Tottenham Hotspur XI: Lloris, Reguilon, Aurier, Rodon, Dier, Hojbjerg, Lo Celso, Ndombele, Moura, Son, Kane
Manchester United XI: Henderson, Wan-Bissaka, Lindelof, Maguire, Shaw, Pogba, Fred, McTominay, Fernandes, Rashford, Cavani
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